Showing posts with label metformin. Show all posts
Showing posts with label metformin. Show all posts

Friday, 15 August 2008

diabetes prevention

More and more research is emerging to support the value of physical activity and a
healthy balanced diet.
In one study, 3234 non-diabetic patients with elevated glucose - a
high-risk population for developing diabetes - were assigned to either a placebo,
metformin or lifestyle modifications. Lifestyle intervention was classified as a
goal of at least 7% weight loss and at 150 minutes of physical activity per week.
The average length of time for follow-up was 2.8 years. Results showed that after
this time the incidence of diabetes had been reduced by 58% in the lifestyle
intervention group as compared to the placebo whereas metformin group had reduced
their incidence of diabetes only 31%.
This has been backed up by numerous other studies and one particular
study suggested that lifestyle interventions could reduce the incidence of disease
by 20% and delay the development of diabetes by 11 years as compared to Metformin
which only resulted in an 8% reduction in disease and delayed onset of diabetes by 3
years.
Another study of lifestyle interventions in people at high risk for
type II diabetes showed sustained lifestyle changes and a reduction in diabetes
incidence that remained after the individual lifestyle counselling was
stopped.